This course for advanced undergrads focuses on Alzheimer's disease research. The first 3 weeks are didactic. The remainder of the course emphasizes a "journal club¿ format where teams of students lead research paper discussions. Assessment: how well students lead/ participate in journal club discussions, periodic quizzes, and a final exam. Requirements: Students must have completed BIOL 3000 AND BIOL 3050 or PSYC 2200 or PSYC 3200. Anti-Requisite: BIOL 4559 topic: Neurodegenerative Diseases.

Introduction to experimental methods in neural development research using zebrafish as a model system. Lectures focus on vertebrate nervous system development and teratogens. Labs build skills in brightfield and fluorescence microscopy, morphological and behavioral analysis, and histology. Course begins with guided inquiry labs and progresses to student-developed scholarly research projects, culminating in presentations of novel research findings.

The goal of this course is to provide an original, unknown outcome research experience in developmental biology. After training in basic methods and descriptions of selected research problems, students form teams and investigate a problem of their choosing. Team members work together in the lab, but each writes an independent research proposal, a notebook, and a final project report on which they are graded. Recommended prerequisites: BIOL 3000 and 3010.

Introduces biological timekeeping as used by organisms for controlling diverse processes, including sleep-wakefulness cycles, photoperiodic induction and regression, locomotor rhythmicity, eclosion rhythmicity, and the use of the biological clock in orientation and navigation. Prerequisite: BIOL 3000 or 3010 or 3020

Why do some diseases become global pandemics, while others die out? What happens to a food web when a species goes extinct? What roles do different organisms have within a social network? How does the structure of brain networks relate to cognitive function? Networks are all around us; we just need to learn to see them. This course will introduce network analysis as a tool for answering fundamental and applied questions across biological disciplines. Coding experience is strongly recommended.

This course uses a case study approach to examine cellular processes that underlie diverse diseases and to identify the relevant molecular components that have been validated or that may serve as new therapeutic targets. We will discuss both established, transformative drugs as well as novel, emerging therapies under development. We will consider socio-economic and demographic issues that impact the accessibility and affordability of new drugs.

This laboratory course provides hands-on experiences with experimental approaches used to study animal behavior. The laboratory exercises explore visual and auditory sensory perception, biological clock, reproductive and aggressive behaviors using actively behaving animals such as hamsters, cichlid fish, crickets and electric fish. Students are given opportunities to design hypothesis-testing experiments in some laboratories.

The process of speciation is fundamental to understanding life's diversity, with implications for how we study evolution, how we define species in nature, and the processes by which they form. In this course, we will explore models of adaptive and non-adaptive speciation and how we test and distinguish among these processes. We will explore examples from biological systems in nature, including syntheses of broad knowledge gained about the speciation process from studying each group of organisms.

This two-lectures-per-week course explores the basic principles of sensory neurobiology. The course consists of four modules. Each module represents one of the senses & consists of an introductory lecture, one or several lectures that will delve into the details of that sense, a current topic lecture on some recent finding, & finally, a guest lecture from a UVa researcher. Completion of BIOL 3050 or PSYC 2200 or PSYC 3200 strongly recommended.

This course focuses on how relatively simple model systems provide the clues as to how certain synaptic connections form and lead to specific behaviors. This will be followed by discussion of how this knowledge can be applied to the understanding and treatment of human neural disorders. 25% of the course is standard lectures and the rest, student-led discussion of primary literature. Prereqs: BIOL 3000 & BIOL 3010; BIOL 3050 or PSYC 2200 or 3200