We will learn to bridge the gap between the fields of bioengineering and the science of how drugs interact with biological systems, i.e., Pharmacology, including the principles of biochemical reaction kinetics and engineering; how such principles can help us describe, model, predict and modulate the outcome of biochemical reactions in cells and biological reactors, and apply these principles to the understanding of pharmacological phenomena. Prerequisites: BME 2104 AND APMA 2130

This course introduces techniques for constructing mathematical and computational models of biological processes. We utilize experimental data to validate those models at many levels of organizational scale -- from genome to whole-tissue. Prerequisites: APMA 2130 or MATH 3250, BME 2101, BME 2104, and BME 2315.

Introduces techniques for constructing mathematical and computational models of biological processes at many levels of organizational scale from genome to whole-tissue. Topics include choice of techniques, quantitative characterization of biological properties, assumptions and model simplification, parameter estimation and sensitivity analysis, model verification and validation and integration of computational modeling w/experimental approaches.Prerequisites: BME 6101, and BME 2104 or BME 7806 (or equivalent).

Applies engineering science, design methods, and system analysis to developing areas and current problems in biomedical engineering. Topics vary by semester.

A year-long research project in biomedical engineering conducted in consultation with a department faculty advisor; usually related to ongoing faculty research. Includes the design, execution, and analysis of experimental laboratory work and computational or theoretical computer analysis of a problem. Requires a comprehensive report of the results. Prerequisite: third- or fourth-year standing, and instructor permission.

In a team, develop, prototype, and conduct verification and validation tests on engineering solutions to clinical challenges, demonstrating concept viability. Formal Design Control, Life Cycle, Risk Analysis, Project Management and Intellectual Property Strategies are introduced. Using Product Development Protocols, prepare a regulatory and implementation pathway analysis for commercialization into clinical practice. Prerequisite: BME 6550 Special Topics: Clinical Technology Continuum of Care

Student led special topic courses which vary by semester

The focus for the course will be establishing a regulatory mindset for students to engage with the Food & Drug Administration, primarily the Center for Medical Devices and Radiological Health. The material covered throughout the semester is presented in a series of lectures, design prompts, exercises, workshops, and reviews. Students will develop their own project(s) and work as individuals and in small groups/teams. Prereq: BME 2000 and BME 2101

How does a single fertilized egg grow and divide into every cell in the body, from branching neurons to beating cardiomyocytes and everything in between? Can we harness this knowledge to better understand disease, and to produce therapeutically relevant cell types, tissues, and organs? You will explore what controls stem cell differentiation using hands-on experiments, with emphasis on methods to engineer cell fate for regenerative medicine. Prerequisite: BME 2104

This course will provide students with a quantitative framework for identifying and addressing important biological questions at the molecular, cell, and tissue levels. The course will focus on the interplay between methods and logic, with an emphasis on the themes that emerge repeatedly in quantitative experiments.