Intro to systems-level measurement techniques for capturing molecular information and the mathematical and computational methods for harnessing the information from these measurements to improve our understanding of cell physiology and disease. Practical implementation of the concepts in MATLAB or Python will be applied to existing, real data from published journal articles. Pre-requisites: APMA 3100 or APMA 3110, BME 2104, BME 2315, and CS 1110 or CS 1111 or CS 1112

This course will provide students with a quantitative framework for identifying and addressing important biological questions at the molecular, cell, and tissue levels. The course will focus on the interplay between methods and logic, with an emphasis on the themes that emerge repeatedly in quantitative experiments.

"We will explore engineering methods to use ""microbes as tools"" for human wellbeing, to understand and combat ""microbes as enemies"" in infectious disease, and to characterize and manipulate ""microbes as partners"" in human health and wellbeing. We will learn how facets of BME are used to test hypotheses of human/microbe relationships and to design strategies to understand and treat disease and improve human wellbeing. Prerequisites: BME 2000 AND (BME 2101 OR BME 2102) AND BME 2104 AND BME 2315"

We will learn to bridge the gap between the fields of bioengineering and the science of how drugs interact with biological systems, i.e., Pharmacology, including the principles of biochemical reaction kinetics and engineering; how such principles can help us describe, model, predict and modulate the outcome of biochemical reactions in cells and biological reactors, and apply these principles to the understanding of pharmacological phenomena. Prerequisites: BME 2104 AND APMA 2130

Introduces biomaterials science and biological interactions with materials with overview of biomaterials testing (in vitro and in vivo) and characterization. Emphasis on emerging novel strategies and design of biomaterials. Areas of concentration include polymers and ceramics in biomaterials, drug delivery, tissue engineering (orthopaedic and vascular) and nanotechnology. Prerequisite: BME 2101, BME 2104, or instructor permission.

Introduces the fundamental principles of tissue engineering. Topics: tissue organization and dynamics, cell and tissue characterization, cell-matrix interactions, transport processes in engineered tissues, biomaterials and biological interfaces, stem cells and interacting cell fate processes and tissue engineering methods. Examples of approaches for regeneration of cartilage, bone, ligament, tendons, skin and liver are presented. Prerequisites: APMA 2130 or MATH 3250 or APMA 2501 - Differential Equations & Linear Algebra, and BME 2101, and BME 2104, or instructor permission.

Applies engineering science, design methods, and system analysis to developing areas and current problems in biomedical engineering. Topics vary by semester. Recent topics include Medical Imaging Systems Theory, BME Advanced Design, BME Electronics Lab, and Systems Biology Modeling and Experimentation. Prerequisite: third- or fourth-year standing or instructor permission.

An overview of modern medical imaging modalities with regard to the physical basis of image acquisition and methods of image reconstruction. Topics cover the basic engineering and physical principles underlying the major medical imaging modalities: x-ray (plain film, mammography, CT), nuclear medicine (PET) and (SPECT), ultrasound, and MRI. Prerequisite: BME 2315, BME 3310, or instructor permission.

Provides a grounding in molecular biology and a working knowledge of recombinant DNA technology, thus establishing a basis for the evaluation and application of genetic engineering in whole animal systems. Beginning with the basic principles of genetics, this course examines the use of molecular methods to study gene expression, deliver viral and non-viral vectors, and its critical role in health. Prerequisite: BME 2101. Co-requisites: BME 2104.

Students will design treatment strategies for cancer and cardiovascular disease based on molecular bioengineering principles. Special topics will include design of nanoparticle drug and gene delivery platforms, materials biocompatibility, cancer immunotherapy, and molecular imaging. Prerequisite: BME 2102 and BME 2315 or instructor permission. Recommended prerequisite: BME 2104 or BME 4414.