Introduces biomaterials science and biological interactions with materials with overview of biomaterials testing (in vitro and in vivo) and characterization. Emphasis on emerging novel strategies and design of biomaterials. Areas of concentration include polymers and ceramics in biomaterials, drug delivery, tissue engineering (orthopaedic and vascular) and nanotechnology. Prerequisite: BME 2101, BME 2104, or instructor permission.

Second part of a year-long course integrating concepts and skills from prior courses to formulate and solve problems in biomedical systems, including experimental design, performance and analysis. Prerequisite: 3rd Year standing in BME major, or instructor permission

"We will explore engineering methods to use ""microbes as tools"" for human wellbeing, to understand and combat ""microbes as enemies"" in infectious disease, and to characterize and manipulate ""microbes as partners"" in human health and wellbeing. We will learn how facets of BME are used to test hypotheses of human/microbe relationships and to design strategies to understand and treat disease and improve human wellbeing. Prerequisites: BME 2000 AND (BME 2101 OR BME 2102) AND BME 2104 AND BME 2315"

Provides biomedical engineers with a grounding in molecular biology and a working knowledge of recombinant DNA technology, thus establishing a basis for the evaluation and application of genetic engineering in whole animal systems. Beginning with the basic principles of genetics, this course examines the use of molecular methods to study gene expression and its critical role in health and disease. Topics include DNA replication, transcription, translation, recombinant DNA methodology, methods for analyzing gene expression (including microarray and genechip analysis), methods for creating genetically-engineered mice, and methods for accomplishing gene therapy by direct in vivo gene transfer. Prerequisite: BME 6103, undergraduate-level cell and/or molecular biology course. (e.g., BME 2104) or instructor permission. Suggested preparation: biochemistry, cell biology, genetics, and physiology..

Provides students with a quantitative framework for identifying and addressing important biological questions at the molecular, cell, and tissue levels. Focuses on the interplay between methods and logic, with an emphasis on the themes that emerge repeatedly in quantitative experiments. Prerequisites: BME 6101 (or equivalent), SEAS graduate student status, or instructor permission.

Introduces genomics and bioinformatics theory and tools to analyze large scale biological data. Specific topics covered are Introduction to Linux and R statistical programming language, computations on the high-performance computational cluster, analysis of sequencing data with applications in gene expression and protein/DNA interactions, differential expression analysis, pathway and co-expression network analysis. Prereq: (APMA 3110 or APMA 3100 or MATH 3100) and (CS 1110 or CS 1111 or CS 1112 with grade of C- or better or successfully completed CS 1110 place-out test) and BME major or minor

Provides students with the skills necessary to engage in meaningful engineering design, and focuses on the latter stages of the engineering design process - detailed design, prototyping, and evaluation. Students develop skills in computer assisted design, embedded controls, prototyping, analysis and teamwork. A major focus of the class is the execution of a design project. Prerequisites: PHYS 1425, and BME major or minor. Recommended Corequisite: PHYS 2415 or ECE 2200.

Applies engineering science, design methods, and system analysis to developing areas and current problems in biomedical engineering. Topics vary by semester. Recent topics include Medical Imaging Systems Theory, BME Advanced Design, BME Electronics Lab, and Systems Biology Modeling and Experimentation. Prerequisite: third- or fourth-year standing or instructor permission.

The course will cover human genetics and genomics, including the human/mammalian genome variation, determination of genomic variation on phenotype and disease risk, mapping and characterizing genetic variants on phenotype, determining the putative impact of genetic variants on gene expression (transcriptomics, epigenomics), the promise and implications of genome science on precision medicine and the ethical, legal & social implications.Pre-requisite: BIOL 3010 or BIOL 4210 or instructor consent.

Second half of a year-long design project required for BME majors. Students select, formulate, & solve a design problem related to a device or a system. Projects use conceptual design, skills obtained in the integrated lab & substantial literature and patent reviews. Projects are sponsored by faculty, physicians and/or companies. Students may work on their own with outside team members when appropriate or with other students in integrative teams. Prerequisite: 4th year standing in the Biomedical Engineering major or instructor permission.