The course will cover human genetics & genomics, including the human/mammalian genome variation; determination of genomic variation on phenotype and disease risk; mapping & characterizing genetic variants on phenotype; determining the putative impact of genetic variants on gene expression (transcriptomics, epigenomics); the promise & implications of genome science on precision medicine; and the ethical, legal, & social implications. Prerequisites: BIOL 3010 or BIOL 4210 or instructor consent.

The Chromatin course modules are designed to provide students with an in-depth understanding of chromatin structure and function. In Chromatin I, the focus will be on chromatin structure and organization, nucleosome and chromatin remodeling factors, and the multiple histone modifying enzymes that regulate DNA-templated cellular functions such as transcription, DNA replication, and repair.

The Chromatin course modules are designed to provide students with an in-depth understanding of chromatin structure and function. Chromatin II will focus on the functional aspects of chromatin organization and regulation. The course will meet two days a week, with time split between faculty presentations that introduce a topic and provide key information, and more interactive sessions that will involve discussions of primary literature.Prerequisite: Restricted to BIMS students or departmental approval required

Research seminars by invited guests and research personnel within the department. All biochemistry graduate students must attend.

A continuing seminar based on papers in the current literature. Participation is required.

For doctoral dissertation, taken under the supervision of a dissertation director.