Deformation and fracture are considered through integration of materials science microstructure and solid mechanics principles over a range of length scales, emphasizing the mechanical behavior of metallic-structural alloys and electronic materials. Metal deformation is understood based on elasticity theory and dislocation concepts. Fracture is understood based on continuum fracture mechanics and microstructural damage mechanisms. Additional topics include fatigue, elevated temperature behavior, material embrittlement, time-dependency, experimental design, damage-tolerant life prognosis, small-volume behavior, and material property modeling.