CHEM 4460
Enzyme Reaction Mechanisms in Human Health and Disease
Course Description
Familiarization with catalytic strategies employed by enzymes and relationship of the strategies to those used in organic chemistry. Reactions discussed include phosphoryl transfer, acyl group activation and transfer, and coenzyme-based catalysis, etc. The understanding of enzyme mechanisms is enhanced by introduction of key insights from kinetics and regulation of enzyme reactions. Emphasis is placed on implications for human health and disease.
