The course will cover human genetics and genomics, including the human/mammalian genome variation, determination of genomic variation on phenotype and disease risk, mapping and characterizing genetic variants on phenotype, determining the putative impact of genetic variants on gene expression (transcriptomics, epigenomics), the promise and implications of genome science on precision medicine and the ethical, legal & social implications.Pre-requisite: BIOL 3010 or BIOL 4210 or instructor consent.